Pharmaceutical Study of Aconitum heterophyllum (Ativisha) Shodhana and Analysis Based on High-Performance Thin-Layer Chromatography and High-Performance Liquid Chromatography
Keywords:
Ativisha, High-performance liquid chromatography, High-performance thin-layer chromatography, Nighantu, Shodhana, SwedanaAbstract
Ativisha (Aconitum heterophyllum), a prominent drug in the Ranunculaceae family, is extensively cited in the
Charaka and Sushruta Samhitas for its therapeutic efficacy. However, its potent diterpene alkaloids necessitate
“Shodhana” (systematic purification) to ensure clinical safety and enhance pharmacological action. This review
examines classical Shodhana protocols and their impact on the plant’s chemical profile, specifically evaluating how
these traditional processes mitigate toxicity. This work highlights the importance of classical Shodhana process in
optimizing the bioavailability of phytochemical metabolites and its impact on the plant’s chemical profile, ensuring
the safety of herbal interventions in primary healthcare.
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