Pharmacognostical and Pharmaceutical Analysis of Dviruttara Hingvadi Churna – An Ayurvedic Herbal Formulation for Purishaja Udavarta by Charaka Samhita

Abstract

Background: In today’s era, the evaluation of the quality of herbal formulations is essential to provide a basis for ensuring their authenticity and quality. Dviruttara Hingvadi Churna is one of the polyherbal formulations that has been explained by Acharya Charaka in his treatise Charaka Samhita for the treatment of Purishaja Udavarta. Despite use in clinical practice, there is a lack of data regarding its pharmacognostical standardization and Physicochemical analysis, which ensures its quality, safety, and reproducibility.

Aim: The study aims to develop the authenticity of Dviruttara Hingvadi Churna through the evaluation of pharmacognostical and physiochemical analysis.

Material and Methods: Pharmacognostical evaluation was carried out at the pharmacognosy department, and pharmaceutical study was carried out at the pharmaceutical department, ITRA, Jamnagar. High-performance thinlayer chromatography (HPTLC) was carried out at Vasu Research Center, Vadodara, Gujarat. 

Results: Pharmacognostical findings confirmed the authenticity and genuine ingredients of Dviruttara Hingvadi Churna. The average values of physicochemical parameters, such as loss on drying – 7.66%, ash value – 3.65%, water soluble extract – 19.44%, alcohol soluble extract – 18.56%, and pH value – 6.5, were analyzed, which were within normal referential range. In the HPTLC study, 4 spots at 254 nm, 6 spots at 366 nm, and 10 spots at 540 nm were obtained.

 Conclusion: The pharmacognostical and Physicochemical analysis of Dviruttara Hingvadi Churna confirmed the purity and genuineness of the drug. This data can serve as reference standards for quality control for future research, supporting their safe and effective therapeutic application.